Department of Biological Science,Graduate School of Science, Hiroshima University

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japnese

Organization

Animal Science Developmental Biology
Cell Biology
Molecular and Cellular Physiology
Plant Biology Plant Taxonomy and Ecology
Plant Molecular Physiology
Plant Molecular Biology and Bioinformatics
Diversity Biology Marine Molecular Biology Marine Biological Laboratory)
Island Biology Miyajima Natural Botanical
Amphibian Biology Bioresource Science Division Amphibian Research Center
Amphibian development
Evolution and Diversity Resulting from the Life Cycle
Plant Genetic Resources Plant Genetic Resources Laboratory of Plant Chromosome and Gene Stock

Animal Science Course

Developmental Biology

Staff/KIKUCHI Yutaka (Professor), HOZUMI Shunya (Assistant Professor), MUTO Akihiko (Assistant Professor (Special Appointment)

The major interest of our laboratory is to clarify the molecular mechanisms of cell fate determination during development and regeneration. For this purpose, we have been focused on two major research projects: (1) studies on the mechanisms of differentiation, trans-differentiation, and dedifferentiation using zebrafish and cell culture system, (2) studies on the mechanisms of transcriptional regulation by chromosomal dynamics.

Key Words Cell fate, Dedifferentiation, Regeneration, Transcriptional regulation

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Cell Biology

Staff/CHIHARA Takahiro(Professor), HAMAO Kozue (Associate Professor),

Our research goal is to reveal how cell society is constructed and maintained during animal development, growth and aging. To this purpose, we are studying the molecular mechanisms of cytokinesis, cell patterning, cell-cell interaction, and the impact of aging on cells/organisms by using sophisticated Drosophila genetic methods, and molecular and biochemical methods with mammalian cell culture system.

Key Words Nervous system, Cytokinesis, Cell patterning, Cell-cell interaction, Aging


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Molecular and Cellular Physiology

Staff/OBARA Masanobu (Professor), UEKI Tatsuya (Associate Professor), MORISHITA Fumihiro (Assistant Professor)

Metal ions are essential for regulation of molecular and cellular physiological functions such as oxygen transfer and storage, redox reaction, electron transfer, drug metabolism, and so on in animal cells. We focus on revealing the molecular mechanism for oxygen metabolism within mammalian cells, accumulation of vanadium in sea squirts, and neuropeptides in sea hares that are mediated by various types of metal-binding proteins.

Key Words Oxygen transfer and storage, Redox reaction, Electron transfer, Drug metabolism, Accumulation of vanadium, Neuropeptides


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Plant Biology Course

Plant Taxonomy and Ecology

Staff/YAMAGUCHI Tomio (Professor), SHIMAMURA Masaki (Associate Professor)

Research in this laboratory concerns taxonomy, phylogeny, morphology and ecology on nonvascular plants including bryophytes, freshwater algae, lichens, and others. The department maintains a research Herbarium (HIRO) which has an extensive bryophyte collection.

Key Words Bryophytes, Cryptogams, Taxonomy, Ecology, Anatomy, Cell biology, Molecular phylogeny


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Plant Molecular Physiology

Staff/TAKAHASHI Yohsuke (Professor), FUKAZAWA Jutarou (Assistant Professor), ITO Takeshi (Assistant Professor (Special Appointment))

This laboratory has focused on the molecular mechanism of cell responses to environmental changes. Our research projects are (1) regulatory mechanisms of gibberellin biosynthesis and signaling, (2) response mechanisms to the environmental stimuli.

Key Words Plant hormone, Transcriptional regulation, Signal transduction, Kinase, Protein-protein interaction


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Plant Molecular Biology and Bioinformatics

Staff/SUZUKI Katsunori (Professor), MORIGUCHI Kazuki (Lecturer), YAMAMOTO Shinji (Assistant Professor (Special Appointment))

Suppose cells obtain genes from entirely different organisms, they can develop new functions rapidly. We focus on phenomena of active gene transfer from bacteria domain to eukarya domain, i.e. T-DNA transport to plants by phytopathogenic agrobacteria, and plasmid DNA mobilization to yeasts by some proteobacteria.

Key Words Horizontal gene transfer, Plasmid DNA, Conjugation, Bacteria, Eukaryotes

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Diversity Biology Course

Marine Molecular Biology (Marine Biological Laboratory)

Staff/TAGAWA Kunifumi (Associate Professor)

Focusing on evolutionary processes of the emergence of basic animal body plans, we take evo-devo studies on cephalochordate lancelets (amphioxus) and enteropneust hemichordates, as well as fossil animals including embryos from the Earliest Cambrian period.

Key Words Evolution, Comparative Developmental Biology, Fossils, Body Pattern, Regeneration


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Island Biology (Miyajima Natural Botanical Garden)

Staff/TSUBOTA Hiromi (Associate Professor)

The Miyajima Natural Botanical Garden is situated along the north coast of Miyajima (Itsukushima) Island, southwestern Japan, ca. 20 km southwest of Hiroshima City. The island is famous as a UNESCO World Heritage Site, and is covered with natural forest and maritime vegetation. Our research projects are island biology, phytogeography, ecology, and conservation biology, utilizing the excellent natural resources of Miyajima Island.

Key Words Island biology, Biodiversity, Phytogeography, Phytosociology, Ecology, Molecular phylogenetics, Cryptogamic botany


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Amphibian Biology Course

Bioresource Science (Amphibian Research Center)

Staff/OGINO Hajime (Professor), IGAWA Takeshi (Assistant Professor), KASHIWAGI Akihiko (Visiting Professor)

We are studying molecular mechanisms of chordate evolution through comparative analysis of gene functions and regulations among the "living fossil" amphioxus, frog and mouse. We are also studying genomic and epigenomic regulation of organ development and regeneration by generating a variety of genetically modified pipid frogs (Xenopus) using leading-edge technologies, such as the high-throughput transgenesis and genome editing.

Key Words Evolution, Development, Regeneration, Comparative Genomics, Epigenetics, Xenopus, Amphioxus, Bioresource, Pathogenic mutations


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Amphibian development (Amphibian Research Center)

Staff/YAOITA Yoshio (Professor), Suzuki Atsushi (Associate Professor), TAKASE Minoru (Associate Professor), FURUNO Nobuaki (Associate Professor), NAKAJIMA Keisuke (Assistant Professor), TAZAWA Ichiro(Assistant Professor)

We focus on the molecular mechanism of amphibian development and the differentiation, development and function of endocrine organs by making use of various techniques in experimental embryology, cell biology, molecular biology, gene engineering and genome editing.

Key Words Oocyte Development and Maturation, Early Development, Regeneration, Metamorphosis,Germ Cell, Environmental Influences


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Evolution and Diversity (Amphibian Research Center)

Staff/MIURA Ikuo (Associate Professor), KURABAYASHI Atsushi (Assistant Professor)

Current amphibian diversity is a product of the life cycle that has evolved since the birth of life. We engage in pioneering research to reveal the processes and mechanisms mediating diversity, and we strive to maintain and preserve diversity across a wide range of biological hierarchies at the gene–genome–chromosome, cell–tissue, individual, population, species, and higher taxonomic levels.

Key Words Evolution, Diversity, Phylogenetic System, Sex and Reproduction, Ecology, Preservation, Genome Biology


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Plant Genetic Resources Course

Plant Genetic Resources (Laboratory of Plant Chromosome and Gene Stock)

Staff/KUSABA Makoto (Professor), TANIGUCHI Kenji (Associate Professor), KOZUKA Toshiaki (Assistant Professor)

We are conserving various Chrysanthemum and cycad species and developing the model species/line of the genus Chrysanthemum. In addition, mutants of the model plant species are isolated and used for the molecular genetic research.

Key Words Genetic resource, Chrysanthemum, Cycad, Model plant, Mutant, Gene function analysis


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Affiliated Facilities

Marine Biological Laboratory

2445 Mukaishima-cho, Onomichi-shi, Hiroshima,
722-0073
http://home.hiroshima-u.ac.jp/rinkai/

Miyajima Natural Botanical Garden

1156-2 Mitsumaruko-yama, Miyajima-cho,
Hatsukaichi-shi, Hiroshima, 739-0543
http://home.hiroshima-u.ac.jp/miyajima/

Institute for Amphibian Biology

1-3-1 Kagamiyama, Higashi-Hiroshima-shi, 739-8526
http://home.hiroshima-u.ac.jp/amphibia/main/InstAmphBiol/Home_en.html

Laboratory of Plant Chromosome and Gene Stock

1-4-3 Kagamiyama, Higashi-Hiroshima-shi, 739-8526
http://home.hiroshima-u.ac.jp/shokui/index.html

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