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Symposium Programs

English is the official language of the symposium. No interpretation services will be provided.

The following sessions are planned for oral and poster presentations:
1. Diagnosis
2. Epidemiology and Pathogenesis
3. Virology and Molecular Biology
4. Disease Control
5. Miscellaneous Topics



November 28, 2006 (Tue)
Registration and Welcome Reception at Mitsui Garden Hotel Hiroshima
(CONFRERE; 25 F)


November 29, 2006 (Wed)
Opening Ceremony
Special Lecture by Dr. Kyle L. Johnson (The University of Texas at El Paso)
Keynote Lectures
Oral Sessions
Poster Sessions (during Lunch Break)
Round Table Discussion (after Oral Sessions)

November 30, 2006 (Thu)
Keynote Lectures
Oral Sessions (during Lunch Break)
Business Meeting (during Lunch Break)
Closing Ceremony
Symposium Banquet at ANA Hotel Hiroshima (22 F)


December 1, 2006 (Fri)
Sympsoium Tour : A-Bomb Dome, National Research Institute of Fisheries and Environment of Inland Sea, and Miyajima where a Wolrd Cultural Heritage, "Itsukushima Shinto Shrine" stands.



Special Speaker


Kyle L. Johnson, Ph.D.

(The
University of Texas at El P
aso)

 

Title:

Alphanodavirus RNA replication and suppression
of RNA interference by protein B2.

 
Profile:

Dr. Kyle L. Johnson obtained a Bachelor of Science in Biology from the University of Washington (Seattle) in 1985. At that time, she became interested in virology and worked with Drs. Akiko Hirano and Tim Wong at the University of Washington and with Dr. Maxine Linial at the Fred Hutchinson Cancer Research Center (Seattle, WA). Her research explored the mechanisms by which avian retroviruses became integrated into the host genome. In 1987, she entered the Ph.D. program in Molecular Biology at the University of Colorado Health Sciences Center in Denver, CO. Under the supervision of Dr. Peter Sarnow (now at Stanford University), her dissertation research focused on the replication of poliovirus RNA.

 

     In 1994, she began postdoctoral training in the Department of Biochemistry at the University of Alabama at Birmingham (UAB). In the laboratory of Drs. Thomas R. Broker and Louise T. Chow, she performed site-directed mutagenesis of several coding regions within the DNA genome of human papillomavirus (HPV) type 11, as an initial step toward establishing a reverse genetic system for HPV. Dr. Johnson returned to RNA virology in 1995 when she moved to the UAB Department of Microbiology for a second postdoctoral fellowship in the laboratory of Dr. L. Andrew Ball. There, her research focused on RNA replication of the alphanodavirus Flock House virus in transfected mammalian cells.

 

     In 1997, Dr. Johnson accepted a position as a Research Assistant Professor in the Department of Microbiology at UAB. While maintaining her collaboration with Dr. Ball’s laboratory, Dr. Johnson shifted her research focus to Nodamura virus (NoV), the type species of the alphanodaviruses. She established a reverse genetic system for NoV, using cloned cDNA copies of NoV genomic RNAs, which functions in a number of cultured mammalian and insect cell lines and in cells of the yeast Saccharomyces cerevisiae. These reagents have facilitated the study of NoV RNA replication and allowed characterization of NoV mutants, including those unable to synthesize the nonstructural protein B2. B2-deficient mutants showed defects in RNA accumulation in both mammalian and insect cells. The severity of these defects differed in a cell-specific manner that correlated with the cell’s ability to mount an RNA interference (RNAi) response. Her collaboration with Dr. Shou-Wei Ding and others showed that NoV B2 suppresses RNAi in transfected insect cells. While at UAB, Dr. Johnson also served as an Associate Scientist in the UAB Comprehensive Cancer Center (1999-2004), an Associate Member of UAB’s Center for AIDS Research (CFAR; 2001-2004), and an Associate Scientist in UAB’s Gregory Fleming James Cystic Fibrosis Research Center (2002-2004).

 

     In October 2004, Dr. Johnson joined the faculty of the University of Texas at El Paso (UTEP) as an Assistant Professor in the Department of Biological Sciences. Her research continues to focus on the mechanism of nodavirus RNA replication, the role of the B2 protein in the nodavirus life cycle, and the suppression of host innate immune responses like RNAi by B2.