Welcome to


広島大学・安倍研究室

Full Power to Produce New Chemistry in 2018!

Arbeitskreise ABE (AK-Abe)

The Research Group of

Professor Dr. Manabu Abe

Đại học Hiroshima · Phòng thí nghiệm Abe

广大学·安倍实验室,廣島大學·安倍實驗室

Universitas Hiroshima · Laboratorium Abe

Research Group of Reaction Organic Chemistry

Department of Chemistry

Graduate School of Science

Hiroshima University, Japan

 
 

News and Announcement


March 30th

Speaker:

Prof. Weston Thatcher Borden

Department of Chemistry,

University of North Texas


Date: Friday, March 30th, 2018

Time: 16:30–17:30

Venue: B301 room, School of Science


Title

Why Are N2 and O2 Unreactive?


Abstract

Experimental heats of formation and enthalpies obtained from G4 calculations both find that the resonance stabilization of the two unpaired electrons in triplet O2, relative to the unpaired electrons in two hydroxyl radicals, amounts to 100 kcal/mol. The origin of this huge stabilization energy is described within the contexts of both molecular orbital (MO) and valence-bond (VB) theory. Although O2 is a triplet diradical, the thermodynamic unfavorability of both its hydrogen atom abstraction and oligomerization reactions can be attributed to its very large resonance stabilization energy. The unreactivity of O2 toward both these modes of self-destruction maintains its abundance in the ecosphere and thus its availability to support aerobic life. However, despite the resonance stabilization of the π system of triplet O2, the weakness of the O−O σ bond makes reactions of O2, which eventually lead to cleavage of this bond, very favorable thermodynamically.

J. Am. Chem. Soc. 2017, 139, 9010−9018.


Congratulations

Unusually Long-wavelength Emissions of Cyclopropanes: New Insight into C–C Bond Homolysis

Manabu Abe,* Kousei Kanahara, Norito Kadowaki, Chun-Jui Tan, and Hui-Hsu Gavin Tsai*

Chemistry - A European Journal, in press


Congratulations

Selective Probing of Potassium Ion in Solution by Intramolecular Excimer Fluorescence of Dibenzo-Crown Ethers

Motoki Kida, Mayuko Kubo, Tomoyuki Ujihira, Takayuki Ebata, Manabu Abe,and Yoshiya Inokuchi*

ChemPhysChem, in press



Prof. Dr. Peter R. Schreiner

Institute of Organic Chemistry,

Justus-Liebig-University, Germany


Date: Monday, March 5th, 2018

Time: 15:30–17:30

Venue: B301 room, School of Science


London Dispersion Effects in Molecular Chemistry – Reconsidering Steric Effects


Abstract

The Gecko can walk up a glass window because of the adhesion in hydrophobic setae on its toes that convey van der Waals (vdW) interactions with the surface. The attractive part of such vdW-interactions is an electron correlation effect referred to as London dispersion. Its role in the formation of condensed matter has been known since the work of van der Waals and London who related dispersion to polarizability. London dispersion has been underappreciated in molecular chemistry as a key element of structural stability, chemical reactivity, and catalysis. This negligence is due to the notion that dispersion is weak, which is only true for one pair of interacting atoms. For increasingly larger structures, the overall dispersion contribution grows rapidly and can amount to tens of kcal mol–1. This presentation shows selected examples that emphasize the importance of inter- and intramolecular dispersion for molecules consisting mostly of first row atoms. We note the synergy of experiment and theory that now has reached a stage where dispersion effects can be examined in fine detail. This forces us to re-consider our perception of steric hindrance and stereoelectronic effects, and even the transferability of chemical bond parameters from one molecule to another.


February 13th

Speaker:

Prof. Dr. Zeev Gross 

Schulich Faculty of Chemistry, Technion – Israel Institute of Technology


Date: Tuesday, Feb 13th, 2018

Time: 15:30–17:30

Venue: B301 room, School of Science


Title:

Metallocorroles for Photocatalysis


Abstract:

Despite of the similarity to porphyrins, focus on the photophysical properties of corroles and their chelates with transition and post-transition metal ions (metallocorroles) started quite late. The most outstanding features appear to be very intense fluorescence (up to twice that of chlorophyll and the ease by which the properties may be tuned by facile synthetic manipulations. Metallocorroles may be designed as to display delayed fluorescence, RT phosphorescence, two-photon absorption, and more. The practical utility of metallocorroles has been exemplified by their use as catalysts for photo-assisted organic reactions, energy-relevant inorganic transformations, photodynamic therapy for fighting cancer, and photodynamic inactivation of microorganisms. Key to success in the above applications is the ability to delicately control the photophysical properties, redox potentials, and the selective positioning of substituents on the macrocycle.


演者

真嶋哲朗先生

大阪大学産業科学研究所・教授


講演タイトル

「単一分子、単一粒子の観測から広がる化学研究」

5研究科共同セミナー


日時: 2018年1月30日(火)、16:00−

場所:理学部B301教室


Speaker

Prof. Dr. Jye-Shane Yang

Department of Chemistry,

National Taiwan University, Taipei,Taiwan


Title

Multi-Stimuli-Responsive and Multicolor Luminescent Organic MaterialsSpeaker:


Date: Wednesday, Jan 17, 2018

Time: 12:50–14:20

Venue: B305 room, School of Science




Congratulations

Artocarmins G−M, Prenylated 4‑Chromenones from the Stems of

Artocarpus rigida and Their Tyrosinase Inhibitory Activities

Mai T. T. Nguyen, Tho H. Le, Hai X. Nguyen, Phu H. Dang, Truong N. V. Do, Manabu Abe,

Ryukichi Takagi, and Nhan T. Nguyen

J. Nat. Prod. 2017, 80, 3172−3178

DOI: 10.1021/acs.jnatprod.7b00453


Welcome to our lab!

Sujan Kumar Sarkar, Agung Dian Pangaribowo, Linh, Tran Bao Nguyen, and Phan Le Bao An


Congratulations

Magnetically Bistable Nitrenes: Matrix-Isolation of Furoylnitrenes in Both Singlet and Triplet States and Triplet 3-Furylnitrene

Feng, Ruijuan; Lu, Yan; Deng, Guohai; Xu, Jian; Wu, Zhuang; Li, Hongmin; Liu, Qian; Kadowaki, Norito; Abe, Manabu; Zeng, Xiaoqing

  1. 1J.Am. Chem. Soc., 2018, in press


Congratulations

Chitose, Y.; Abe, M.

Two-photon Responsive Caged Compounds

2光子応答性ケージド化合物

光化学協会誌、2018, 印刷中


Congratulations

Photochemical [2+2] cycloaddition reaction of enone derivatives with 2-siloxy-1H-pyrrole derivatives

Xue, J.; Takagi, R.; Abe, M.

ARKIVOC, 2017, in press

Special Issue for Professor Ken Lalli


Congratulations

Zhuang Wu; Ruijuan Feng; Hongmin Li; Jian Xu; Guohai Deng; Manabu Abe, Dr.; Didier Bégué, Dr.; Kun Liu, Dr.; Xiaoqing Zeng

Angew. Chem. Int. Ed., 2017, in press.

https://www.chemistryworld.com/news/huge-molecular-fragment-quantum-tunnels-in-everyday-lab-reaction/3008209.article


Congratulations

Wan, Huabin; Xu, Jian; Liu, Qian; Li, Hongmin; Lu, Yan; Abe, Manabu; Zeng, Xiaoqing

The Journal of Physical Chemistry, 2017, in press.


Congratulations

Abe, M.; Akisaka, R.

Is π Single Bonding Possible? A Challenge in Organic Chemistry

Chem. Lett., 2017, 46, 1586. doi:10.1246/cl.170711


Welcome to our lab!

Wang Zhe from China and Nguyen Hai Dang from Vietnam


Congratulations

Satish, for your PhD degree!


Congratulations

B(MIDA)-Containing Diborons

Yoshida, Hiroto; Seki, Michinari; Kageyuki, Ikuo; Osaka, Itaru; Hatano, Sayaka; Abe, Manabu

ACS Omega, in press


Congratulations

Using Laser Flash Photolysis to Elucidate Solid-State Reaction Mechanism of α-Azido-p-Methoxyacetophenone

Sujan K. Sarkar, DeVonna M. Gatlin, Anushree Das, Breyinn Loftin, Jeanette A. Krause, Manabu Abe and Anna D. Gudmundsdottir

Org. Biomol. Chem., in press.


Congratulations

Is π–Single Bonding (C–π–C) Possible? A Challenge in Organic Chemistry

Manabu Abe* and Rikuo Akisaka

Chem. Lett., in press, Highlight Review


Congratulations

Two ring opened oxetane taxoids containing a C-20 benzoyloxy group from the roots of Taxus wallichiana Zucc.

Dang, Phu H.; Nguyen, Hanh H. T.; Truong, Hien T. T.; Do, Truong N. V.; Nguyen, Hai X.; Nguyen, Mai T. T.; Abe, Manabu; Takagi, Ryukichi; Nguyen, Nhan T.

Tetrahedron Letters (2017), 58(40), 3897-3900.


Congratulations

Design and Synthesis of Two-Photon Responsive Chromophores for Near-Infrared Light Induced Uncaging Reactions

Manabu Abe*, Youhei Chitose, Satish Jakkampudi, Pham Thi Thu Thuy, Qianghua Lin, Bui Thi Van, Ayato Yamada, Ryoko Oyama, Miyu Sasaki, Claudine Katan*

Mini-Review, Synthesis, in press, special issue of Herbert Mayr’s 70th birthday


Seminar Announcement


Speaker:

Prof. Dr. John C.-G. Zhao

University of Texas at San Antonio, USA


Date: Tuesday, June 27, 2017

Time: 14:30-

Venue: B301 room, School of Science


Title:

Asymmetric Catalysis with Modularly Designed Organocatalysts


Abstract:

Modularly designed organocatalysts (MDOs) are organocatalysts that are self-assembled in the reaction medium directly from properly designed precatalyst modules. The structures of these catalysts are easy to modify and a library of catalysts can be created by simple permutations of the precatalyst modules without any synthetic step.  I this presentation, we will demonstrate that MDOs are excellent catalysts for many organic reactions. Most significantly, with properly designed systems, diastereodivergent catalysis can also be readily achieved by using MDOs.


Congratulations

N-Methylcarbamoyl Azide: Spectroscopy, X-ray Structure and Decomposition via Methylcarbamoyl Nitrene

Huabin Wan, Hongmin Li, Jian Xu, Zhuang Wu, Qifan Liu, Xianxu Chu, Manabu

Abe,* Didier B.gu. and Xiaoqing Zeng*

Organic Chemistry Frontiers, in press


Congratulations

Design and Synthesis of Two-Photon Responsive Chromophores for Near-Infrared Light Induced Uncaging Reactions

Manabu Abe,* Youhei Chitose, Satish Jakkampudi, Pham Thi Thu Thuy, Lin Qianghua, Bui Thi Van, Ayato Yamada, Ryoko Oyama, Miyu Sasaki, and Claudine Katan*

SYNTHESIS, in press

Special Issue for Herbert Mayr’s 70th Birthday



Speaker:

Prof. Dr. Chryssostomos Chatgilialoglu

ISOF, Consiglio Nazionale delle Ricerche, Bologna,

Italy


Date: Tuesday, May 23, 2017

Time: 16:20-

Venue: E002 room, School of Science


Title:

Biomimetic Radical Chemistry


Abstract:

Free radical production in biological systems is the subject of a very lively scientific debate, focusing on type and extent of damages, as well as on the efficiency of protective and repair systems. Molecular mechanisms and targets of reactive radical species can be studied using biomimetic models, which allow the experiments to be performed in a simplified environment, but suitably designed to be in strict relationship with cellular conditions. By this approach, free radical processes such as lipid isomerization in cell membranes, cyclopurines formation in DNA, and protein desulfurization have been studied in our laboratory, finalizing this research toward biomarker discovery. Ongoing projects will be described with some examples.


Congratulations

Computational Study on 1,3-Disilacyclobutane-1,3-diylidene Disilylenes: A Synthetic Strategy for cis-Bent Disilenes

Yoshiki Fujita and Manabu Abe*

Journal of Physical Organic Chemistry, in press

Special Issue for Waldemar Adam’s 80th Birthday


Congratulations

Design and Synthesis of a Caged Carboxylic Acid with a Donor-π-Donor Coumarin Structure: One-photon and Two-photon Uncaging Reactions Using Visible and Near-Infrared Lights

Chitose, Youhei; *Abe, Manabu; Furukawa, Ko; Lin, Jhe-Yi; *Lin, Tzu-Chau; *Katan, Claudine

Organic Letters, in press


Congratulations

Direct observation of methoxycarbonylnitrene

Hongmin Li, Zhuang Wu, Dingqing Li, Huabin Wan, Jian Xu, Manabu Abe and Xiaoqing Zeng*

Chemical Communications, in press



Welcome


Iris (from Ruhr Univ Bochum, Germany) for your stay in our Lab.


DeVonna (from University of Cincinnati, USA) and Philipp (LMU München, Germany) for your stay in our Lab!



News


Ichiki, Onishi, Fujita, Shimokawa, and Takeuchi graduated from our Lab on March 23rd.


Oyama, Sasaki, Tanabe, and Miyahara joined to our Lab on March 1st.


Dr. José Paulo Da Siva will give a talk on March 21st 2017

Analytical and biological applications of molecular nanocontainers

Speaker:

Dr. José Paulo Da Silva

Universidade do Algarve

Faro, Portugal

Date: Tuesday, March 21, 2017

Time: 10:00-11:30

Venue: B305 room, School of Science


Manabu Abe gives a talk at Würzburg University, Germany, February 28-30, 2018.


Manabu Abe gives a talk at Edinburg University, UK, Sept 11, 2017.


Manabu Abe gives a talk at ESOR 1017 in Durham, UK, Sept 3-8, 2017.

https://www.dur.ac.uk/chemistry/events/esor.2017/


Manabu Abe gives a talk at International Symposium on Dynamics and Intermediates of Molecular Transformations in München, Germany, August 2-4, 2017.


Manabu Abe gives a talk at PSRC-8 in Brisbane, July 18-22, 2017.

https://psrc2017.com


Manabu Abe gives a talk at BioTech conference in Tokyo, June 30 2017.

http://www.bio-t.jp/ja/


Manabu Abe gives a talk at ISRIUM 2017, June 18-22 2017, in Sorrento Italy.

http://web.colby.edu/isrium2017/


Manabu Abe gives a talk at 15th Zimmer International Scholar Program Symposium at University of Cincinnati on March 27th 2017.

http://artsci.uc.edu/departments/chemistry/alumni-and-community/zimmer-program/2013-zimmer-scholar-schedule-of-events.html


Our students present their research studies at the annual meeting of Chemical Society of Japan in March 16-19 in Yokohama:

Xue (2F3-33); Yoshidomi (1F5-12); Akisaka (1F5-10); Chitose (2F3-50); Matsumoto (3F6-02); Yamasaki (4E5-04); Kadowaki (1F5-09); Takeuchi (2PC-070); Tabuchi (3E6-28); Yamada (2F3-51)

http://www.csj.jp/nenkai/97haru/


Press release


Our research study on “Caged Calcium” was press released in AlphaGalileo.

http://www.alphagalileo.org/ViewItem.aspx?ItemId=172204&CultureCode=en


Congratulations

Suplatast tosilate protects the lung against hyperoxic lung injury by scavenging hydroxyl radicals

Kazuhide Fukuhara, Taku Nakashima; Manabu Abe; Takeshi Masuda; Hironobu Hamada; Hiroshi Iwamoto; Kazunori Fujitaka; Nobuoki Kohno; Noboru Hattori

Free Radical Biology & Medicine, in press


Congratulations

Mechanistic Study of Stereoselectivity in Azoalkane Denitrogenations

M. Abe* and S. Hatano

Pure and Applied Chemistry, in press


Congratulations, Yoshidomi-kun and Mishima-san, for your publication in Angew. Chem.

Direct Detection of a Chemical Equilibrium between a Localized Singlet Diradical and Its σ-Bonded Species by Time Resolved UV-vis and IR Spectroscopy: Notable Nitrogen-Atom Effects

  1. 1S.Yoshidomi, M. Mishima, S. Seyama, M. Abe*, Y. Fujiwara, T. Ishibashi*

Angew. Chem. Int. Ed., in press, DOI: 10.1002/anie.201612329 and 10.1002/ange.201612329


Congratulations, Xue-kun for your excellent student scholarship!


Congratulations, Ueda-san and Komori-kun, for your publication in Supramolecular Chemistry

Light-harvesting organogel based on tris(phenylisoxazolyl)benzene

Toshiaki Ikeda, Yuko Ueda, Naomitsu Komori, Manabu Abe, and Takeharu Haino*

Supramolecular Chemistry, in press


Congratulations, Ogihara-kun, your paper was accepted for publication in CEJ!!!

Control of the termination mechanism in radical polymerization by viscosity: Selective disproportionation in viscous media

Yasuyuki Nakamura, Tasuku Ogihara, Sayaka Hatano, Manabu Abe, and Shigeru Yamago*

in Chemistry - A European Journal, in press,


Congratulations, Sujan-kun, your paper was accepted for publication in JACS!!!

Using Molecular Architecture to Control the Reactivity of a Triplet Vinylnitrene

Sarkar, Sujan; Osisioma, Onyinye; Karney, William; Abe, Manabu; Gudmundsdottir, Anna

in Journal of the American Chemical Society, in press, ja-2016-05746c


Lin-kun, Duyen-san, Van-san, welcome to our lab!


Congratulations, Xue-kun for your Poster Award at T The 27th Annual Meeting of The Society of Physical Organic Chemistry, Japan, September 1-3

http://home.hiroshima-u.ac.jp/poc27/index.html


The 27th Annual Meeting of The Society of Physical Organic Chemistry, Japan, September 1-3 at International Convention Center in Hiroshima, will be organized by AK-Abe.


Homepage: http://home.hiroshima-u.ac.jp/poc27/index.html


IUPAC International Conference on Physical Organic Chemistry in Sydney:

http://www.icpoc23.unsw.edu.au


Congratulations, Xue-kun, your paper was accepted for publication in JPOC!!!

Photochemical [2+2] Paternò-Büchi Cycloaddition of Aromatic Carbonyl Compounds with 2-Siloxy-1H-Pyrrole Derivatives

Jianfei Xue, Manabu Abe, Ryukichi Takagi

in Journal of Physical Organic Chemistry, in press


Congratulations, Satish-kun, your paper was accepted for publication in ACS Omega!!!

Design and Synthesis of a 4-Nitrobromobenzene Derivative bearing an Ethylene Glycol Tetraacetic acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region, and Their Application In Vivo

Jakkampudi, Satish; Abe, Manabu; Komori, Naomitsu; Takagi, Ryukichi; Furukawa, Ko; Katan, Claudine; Sawada, Wakako; Takahashi, Noriko; Kasai, Haruo

in ACS Omega, in press


Congratulations, Chitose-kun, your paper was accepted for publication in Chemistry Letters!!!

Design, Synthesis, and Reaction of π-Extended Coumarin-Based New Caged Compounds with Two-Photon Absorption Character in the Near-IR Region

Chitose, Youhei; Abe, Manabu; Furukawa, Kou; Katan, Claudine

in Chemistry Letters, in press


Congratulations, Tada san and Mizuno kun, your paper was accepted for publication in JCP-B!!!

Impact of Diradical Spin State (Singlet vs. Triplet) and Structure (Puckered vs. Planar) on the Photodenitrogenation Stereoselectivity of 2,3-Diazabicyclo[2.2.1]heptanes

Abe, Manabu; Tada, Saori; Mizuno, Takemi; Yamasaki, Katsuyoshi

in  The Journal of Physical Chemistry, in press


Congratulations, Fujita-kun, your paper was selected as Selected Paper in BCSJ!!!

Computational Study of Cyclobutane-1,3-diylidene Dicarbenes: Ground-State Spin Multiplicity and New Strategy Toward the Synthesis of Bicyclo[1.1.0]but-1(3)-enes

in Bulletin of the Chemical Society of Japan, in press, dx.doi.org/doi:10.1246/bcsj.20160051


Congratulations, Satish for your Poster Award at The 26th IUPAC Photochemistry

April 3-8, 2016, Osaka, Japan

http://web.apollon.nta.co.jp/iupac2016/



The following International Symposium will be organized by AK-Abe

(1)Pre-Symposium of IUPAC Photochemistry in Hiroshima

April 1-2, 2016

Http://web/apollon.nta.co.jp/iupac2016/scientific.html

Hiroshima City Bunka Koryu Kaikan

Invited Speakers:

    Thorsten Bach (TU Munich, Germany)

    Cornelia Bohne (Victoria, Canada)

    Axel Griesbeck (Cologne, Germany)

    Anna Gudmundsdottir (Cincinnati, USA)

    Norbert Hoffmann (Reims, France)

    Petr Klan (Masaryk, Czech)

    Dongho Kim (Yonsei, Korea)

    Tadashi Mori (Osaka, Japan)

    Henrik Ottoson (Uppsala, Sweden)

    Sabine Richard (Oxford, UK)


(2) Pre-Symposium of the 70th Fujihara Seminar in Hiroshima

Faculty Club, Hiroshima University, Higashi-Hiroshima city

April 16, 2016

    Invited Speakers:

    Igor Alabugin (Noth Florida, USA)

    Shinro Yasui (Tedukayama, Japan)

    Herbert Mayr (LMU Munich, Germany)

    Satoshi Usui (Niigata Univ, Japan)

    Ian H Williams (Bath Univ., UK)

    Yiitzhak Apeloig (Technion, Israel)

    Kazuhide Nakata (Hosei Univ, Japan)

    Shuhei Itoh (Chiba, Japan)

    Satoshi Satoh (Rikkyo, Japan)

    Zvi Rapport (The Hebrew Uni, Israel)

    Curt Wentrup (Queens Uni, Australia)

    Peter Schreiner (Giessen Univ, Germany)


Congratulations, Yo-kun for your publication:

A Puckered SInglet Cyclopentane-1,3^diyl–Detection of the Third Isomer in Homolysis

in Chem. Eur. –J. in press, inside cover, chem201503975.

Highlighted on the Chemistry Views: http://www.chemistryviews.org/details/ezine/8658601/Freeze_Framing_the_Third_Isomer_of_CC_Homolysis.html


Congratulations, Komori kun and Satish kun for your publication:

Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light

in Chemical Communications, in press, DOI: 10.1039/C5CC07664A


Congratulations, Fujita-kun for your publication:

Computational Study of Cyclobutane-1,3-diylidene Dicarbenes: Ground-State Spin Multiplicity and New Strategy Toward the Synthesis of Bicyclo[1.1.0]but-1(3)-enes

in Bulletin of the Chemical Society of Japan, in press, dx.doi.org/doi:10.1246/bcsj.20160051


Congratulations, Norbert for your publication:

The structure of electronically excited a,ß-unsaturated lactones

in Journal of Physical Organic Chemistry, in press,

 

1-3-1 Kagamiyama, Higashi-Hiroshima City, Hiroshima 739-8526, Japan

E-mail: mabe at hiroshima-u.ac.jp

tel & fax: 082-424-7432

+81-82-424-7432 (International)