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["Excel_PkPd Ver1.41 for PaperChart This Program was Developed by Ryuji Nakamura (r_nacamura@yahoo.co.jp)",{"$nulls":74},"Parameter List (Referred to  \"PropofolMon\" which was developed by Dr. M.Nakao)"]
["Drug selection",{"$nulls":74},"Label","1 Fentanyl_Shafer","2 Remifentanil_Minto","3 Propofol_Marsh","4 Propofol_Schnider","5 Kataria Paed","6 Paedfusor1-12yr","7 Paedfusor13yr","8 Paedfusor14yr","9 Paedfusor15yr","10 Paedfusor16yr","11 Rocuronium","12 Dexmedetomidine","13 DEX_ paed_Diaz","14 DEX_ paed_Petroz","15 DEX_paed_Potts","16 DEX_paed_Pooled","17 DEX_paed_Vilo<2yo","18 DEX_paed_Vilo>2yo","19 Blank","20 Blank","21 Blank","22 Blank","23 Blank","24 Blank","25 Blank","26 Blank","27 Blank","28 Blank","29 Fentanyl 2","30 Remifentanil 2"]
["1 Fentanyl_Shafer",null,null,">R U N",null,null,"Bolus Dose","Constant\nrate","TCI",null,"Manual",{"$nulls":4},"Bolus",{"$nulls":6},"Continuous",{"$nulls":8},"Runge Kutta Calculation",{"$nulls":20},"TCI calculation",{"$nulls":22},"Number",1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30]
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[{"$nulls":75},"Concentration（Unit 1/mL)",50,100,10,10,10,10,10,10,10,10,10,4,4,4,4,4,4,4,{"$nulls":10},50,100]
["Max pump Speed (ml/h)",1200,{"$nulls":73},"V2",{"v":24.242647058823533,"d":"24.243"},8.284,{"v":23.62909090909091,"d":"23.629"},{"v":23.982999999999997,"d":"23.983"},{"v":50.5,"d":"50.500"},{"v":47.46545454545455,"d":"47.465"},{"v":41.45454545454546,"d":"41.455"},{"v":35.443636363636365,"d":"35.444"},{"v":29.432727272727274,"d":"29.433"},{"v":23.62909090909091,"d":"23.629"},{"v":3.634615384615384,"d":"3.635"},{"v":13.803127672571776,"d":"13.803"},{"v":60.139541056713725,"d":"60.140"},{"v":49.95,"d":"49.950"},{"v":48.714285714285715,"d":"48.714"},{"v":49.285714285714285,"d":"49.286"},{"$nulls":12},{"v":50.42752867570386,"d":"50.428"},{"v":9.899544748365122,"d":"9.900"}]
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[]
[{"$nulls":75},"Covariants","Wt","LBM,Gender,Age","Wt","Wt","Wt","Wt","Wt","Wt","Wt","Wt","Wt","Ht","Wt","Wt","Wt,Age","Wt, Age","Wt","Wt",{"$nulls":11},"Wt"]
[{"$nulls":75},"PeparChart label","ﾌｪﾝﾀ","ｱﾙﾁﾊ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ","ﾃﾞｨﾌﾟ",{"$nulls":18},"ﾌｪﾝﾀ","ｱﾙﾁﾊ"]
[]
[{"$nulls":75},"Manual",{"$nulls":11},"t1/2a(hr)",0.17]
[{"$nulls":75},1,"Select a drug name.",{"$nulls":5},"Drug selection",{"$nulls":4},"t1/2b(hr)",2.65]
[{"$nulls":75},2,"Decide which of TCI and Constant rate infusion you give priority to.",{"$nulls":5},"Method selection",{"$nulls":4},"CL(L/hr/kg)",0.58]
[{"$nulls":75},3,"Input settings.",{"$nulls":5},"Settings",{"$nulls":4},"V1(L/kg)",0.44]
[{"$nulls":75},4,"Decide units of bolus and continuous rate infusion.",{"$nulls":5},"Units",{"$nulls":4},"V2(L/kg)",1.09]
[{"$nulls":75},5,"Input drug dose.",{"$nulls":5},"Dose",{"$nulls":4},"Vss(L/kg)",1.53]
[{"$nulls":87},"α",0.06795560593724953]
[{"$nulls":75},"*","If you want to use new parameters, you can use \"Blank\" cells.",{"$nulls":5},"Here",{"$nulls":4},"β",0.004359416229936764]
[{"$nulls":76},"In new parameters, you should input all rate constants(k10 to ke0) ,\"V1\" and \"Concentration\"",{"$nulls":10},"K10",0.02196969696969697]
[{"$nulls":75},"*","Values of column M and N are calculated concentrations.",{"$nulls":5},"Cp and Ce",{"$nulls":4},"K12",0.03686098939410301]
["患者名",{"$nulls":75},"If you want to make another chart, please select the columns as data.",{"$nulls":10},"K21",0.013484335803386318]
["開始日",{"$nulls":88},"在胎週数（Week)",40,40]
["読み込みファイル名",0,{"$nulls":87},"PMA（Week)",1960,1960]
["ログファイルの場所",0,{"$nulls":87},"N",2.78,2.56]
[{"$nulls":89},"TM50",46.5,44.5]
[{"$nulls":89},"CLstd",39.2,42.1]
["シート行数",5,{"$nulls":87},"V1std",36.9,56.3]
["手術室番号","0",{"$nulls":87},"Qstd",69.9,78.3]
[{"$nulls":89},"V2std",68.2,69]
[{"$nulls":89},"週数による補正",0.9999695887603902,0.9999381130317982]
["Total Bolus","0 mcg",{"$nulls":87},"Finf(0.73)",1,1]
["Total Continuous","0 mcg/mL"]
[]
["Parameters"]
["Drug Name","Fentanyl_Shafer"]
["k10",0.0827]
["k12",0.471]
["k13",0.225]
["k21",0.102]
["k31",0.006]
["ke0",0.114]
["v1(L)",5.25]
["Concentration （mcg/ml）",50]
["Unit of dose","mcg"]
["Unit of concentration","ng"]
["Constant rate / timestep"]
["k10",0.1654]
["k12",0.942]
["k13",0.45]
["k21",0.204]
["k31",0.012]
["ke0",0.228]
[]
["Max constant rate",1000000]
["Mode",3]
["PaperChart Label","ﾌｪﾝﾀ"]
[]
[]
["List source"]
["Dominant method","1.Constant rate"]
[null,"2.Target concentration"]
[null,"3.Const>Target"]
[null,"4.Target>Const"]
[]
["Timing sheet","1.Use Timing Sheet"]
[null,"2.Input This Sheet"]
[]
["Gender","M"]
[null,"F"]
[]
["Time step",1]
[null,10]
[null,30]
[null,60]
[null,120]
[null,300]
[]
[]
[]
[]
[]
[12]
["12:43:49"]
[5]

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[]
[null,null,"ログファイル簡易指定ボタン",{"$nulls":4},"注意事項"]
[{"$nulls":7},"開いているシートだけが逐次更新されています。"]
[{"$nulls":7},"ほかのシートは開いたときに新しく読み込みなおします。"]
[{"$nulls":3},"このボタンはリアルタイムシミュレーション専用です。",{"$nulls":3},"2010-06-28","すべてのシートを逐次更新するように変更しました。"]
[{"$nulls":3},"手術室番号とその手術室での症例の例数、現在の日時からログファイルを決定します。"]
[{"$nulls":7},"各シートのファイル名欄に直接ファイル名を記述すると、そのファイルを読みに行きます。"]
[null,null,"初期設定の方法"]
[]
[null,"１）","Excel_PkPdのパラメーターを調整する。"]
[{"$nulls":3},"右側にExcel_PkPdをスクロールすると出てきます。",{"$nulls":3},"大まかな使い方"]
[{"$nulls":3},"特に変更する必要はありません",{"$nulls":3},"PaperChartと連携する場合は、初期設定後にログファイルを指定して、AUTO modeで開始します。"]
[{"$nulls":3},"新しいパラメーターを追加する場合、白抜きの部分は最低埋めてください。",{"$nulls":3},"PaperChartのログファイルを後日確認する場合は、ログファイルを指定後にReloadで読み込みます。"]
[null,"２）","PaperChartで使用しているラベルを指定する"]
[{"$nulls":3},"ラベルは半角カタカナで指定してください。",{"$nulls":3},"オフラインシミュレーターとして使う場合、シートを必要なだけ増やして、OFFLINE modeで開始します。"]
[{"$nulls":3},"ラベルがほかのラベルに包含される場合、短いほうが長いほうを拾ってしまうことがあります。"]
[{"$nulls":3},"（”ﾌｪﾝﾀ”と”ﾌｪﾝﾀﾆﾙ”というラベルがある場合、”ﾌｪﾝﾀ”のシートが”ﾌｪﾝﾀﾆﾙ”を拾うことがあります。）",{"$nulls":3},"リアルタイムシミュレーションでない場合は、ボタンを押す必要はありません。"]
[{"$nulls":7},"入力内容を一括消去したい場合は、ログファイルを指定していない状況でReloadをします。"]
[null,"３）","手術室の番号を指定する",{"$nulls":4},"（エラーメッセージが出ますが、無視します）"]
[null,null,"手術室番号",1]
[null,"４）","ログファイルのパスを決定するため、サーバー内のログファイルを一つ指定する。"]
[]
[]
[null,null,"ログファイルの場所"]
[null,null,"読み込みファイル名"]
[null,"５）","Excel_PkPdシートのシート行数変更ボタンでシートの行数を必要なだけ伸ばしておく。"]
[{"$nulls":3},"配布時にはファイルサイズを小さくするために最小限に縮めています。"]
[{"$nulls":3},"シートの保護をしていると伸ばせません。"]
[null,"６）","Excel_PkPdシートを必要な薬剤の数だけコピーして増やす"]
[{"$nulls":3},"Excel_PkPd(2), Excel_PkPd(3)….."]
[{"$nulls":3},"コピー元は常に”Excel_PkPd”シートにしたほうがいいでしょう。"]
[null,"７）","各シートの薬剤名をきめる。"]
[null,"８）","どこかのシートでAUTOボタンを押すか、それぞれのシートでRefreshボタンを押すとデータが読み込まれます。",{"$nulls":4},"自動更新の時間間隔です。"]
[{"$nulls":7},"もし負荷が高すぎるようでしたら、延ばしてください。"]
[{"$nulls":7},10]
{"$rows_empty":106}
[{"$nulls":9},0]
[]
[{"$nulls":9},0]