研究業績

Research Articles

2024

Tanaka S., Matsushita Y., Hanaki Y., Higaki T., Kamamoto N., Matsushita K., Higashiyama T., Fujimoto K., Ueda U.
"HD-ZIP IV genes are essential for embryo initial cell polarization in the radial axis initiation in Arabidopsis"
Curr. Biol. (2024)
プレスリリース 広島大学.
Matsumoto M, Matsushita K, Hane M, Wen C, Kurematsu C, Ota H, Bang Nguyen H, Quynh Thai T, Herranz-Pérez V, Sawada M, Fujimoto K, García-Verdugo JM, Kimura KD, Seki T, Sato C, Ohno N, Sawamoto K. N
"Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function"
EMBO molecular medicine (2024)
Fujikake Y., Fukuda K., Iwatani Y., Matsushita K., Fujimoto K., Nishino A. S.
"Pulsation waves along the Ciona heart tube reverse by bimodal rhythms expressed by a remote pair of pacemakers"
J. Exp. Biol. (2024) jeb.246810.
プレスリリース 広島大学.
Nakatani T., Utsumi Y., Fujimoto K., Iwamura M., Kise K.
"Image recognition-based petal arrangement estimation"
Frontiers Plant Sci. (2024)
Sudo M., Fujimoto K.
"Diffusive mediator feedbacks control the health-to-disease transition of skin inflammation"
PLOS Comp. Biol. 20(1): e1011693 (2024)
プレスリリース 広島大学.

2023

Sarper S.,Kitazawa M. S., Fujimoto K.
"Size-correlated polymorphisms in phyllotaxis-like periodic and symmetric tentacle arrangements in hydrozoan Coryne uchidai"
Front. Cell Dev. Biol. (2023)
プレスリリース 広島大学.
Tsuboi A., Fujimoto K., Kondo T.
"Spatiotemporal remodeling of extracellular matrix orients epithelial sheet folding"
Science Advances 9 eadh2154 (2023)
Press release 広島大学. Eureka Alert.
Horibe K., Taga G., Fujimoto K.
"Geodesic theory of long association fibers arrangement in the human fetal cortex"
Cerebral Cortex 33(17) 9778-86(2023)
プレスリリース 広島大学. 阪大ReSOU.
Fujiwara M., Imamura M., Matsushita K., Roszak P., Yamashino T., Hosokawa Y., Nakajima K., Fujimoto K., Miyashima S.
"Patterned proliferation orients tissue-wide stress to control root vascular symmetry in Arabidopsis"
Curr. Biol. (2023)
プレスリリース 阪大ReSOU.
Ikejiri Y., Tanimoto Y., Fujita K., Hiramatsu F., Yamazaki S. J., Endo Y., Iwatani Y., Fujimoto K., Kimura K. D.
"Neural mechanism of experience-dependent sensory gain control in C. elegans"
Neuroscience Research (2023)
プレスリリース 阪大ReSOU.
Ishikawa M., Fujiwara A., Kosetsu K., Horiuchi Y., Kamamoto N., Umakawa N., Tamada Y., Zhang L., Matsushita K., Palfalvi G., Nishiyama T., Kitasaki S., Masuda Y., Shiroza Y., Kitagawa N., Nakamura T., Cui H., Hiwatashi Y., Kabeya Y., Shigenobu S., Aoyama T., Kato K., Murata T., Fujimoto K., Benfey P. N., Hasebe M., Kofuji R.
"GRAS transcription factors regulate cell division planes in moss overriding the default rule"
Proceedings of the National Academy of Sciences USA(2023)
プレスリリース 阪大ReSOU.

2022

Matsushita K., Hashimura H., Kuwayama H., Fujimoto K.
"Collective Cell Movement under Cell-Scale Tension Gradient at Tissue Interface"
J. Phys. Soc. Jpn. 91, 054802(2022)
Goh T., Fujiwara M., Tsugawa S., Fujimoto K.
"器官の形に種を超えた共通性をもたらす物理"
生物物理62巻1号 p.7-12 (2022)
Sudo M., Fujimoto K.
"Traveling wave of inflammatory response to regulate the expansion or shrinkage of skin erythema"
PLOS ONE (2022)
プレスリリース 阪大ReSOU.

2021

Matsushita K., Kamamoto N., Sudo M., Fujimoto K.
"Interface Effect on Persistence of Cellular Mutually Guiding"
Proc. Sympo. Simul. Traffic Flow Self-Driven Part. (2021)
Sarper S.E., Hirai T., Matsuyama T., Kuratani S., Fujimoto K.
"Polymorphism in the symmetries of gastric pouch arrangements in the sea anemone D. lineata."
Zoological Lett. (2021) DOI: 10.1186/s40851-021-00180-0
プレスリリース 阪大ReSOU.
プレスリリース 理化学研究所.
Matsushita K., Yabunaka S. Fujimoto K.
"Polarity Fluctuation Inhibition by Memory in Collective Cell Motion"
J. Phys. Soc. Jpn.(2021) DOI: 10.7566/JPSJ.90.054801
Kamamoto N. , Taishi T., Fujimoto K., Shimamura M.
"Rotation angle of stem cell division plane controls spiral phyllotaxis in mosses."
J. Plant. Res.(2021) DOI: 10.1007/s10265-021-01298-0
Fujiwara M., Goh T., Tsugawa S., Nakajima K, Fukaki H.,Fujimoto K.
"Tissue growth constrains root organ outlines into an isometrically scalable shape."
Development(2021) DOI:10.1242/dev.196253
  
プレスリリース 阪大ReSOU.

2020

Katsuyoshi M. , Yabunaka S., Hashimura H., Fujimoto K.
"Leader-guiding collective cell rotation"
Proceedings of the Symposium on Simulation of Traffic Flow and Self-driven Particles(2020)
Katsuyoshi M.
"Adhesion-stabilizing long-distance transport of cells on tissue surface"
Phys. Rev. E.(2020) DOI:10.1103/PhysRevE.101.052410
Okuda S., Fujimoto K.
"A Mechanical Instability in Planar Epithelial Monolayers Leads to Cell Extrusion."
Biophys. J. (2020)
Kitazawa M. S., Fujimoto K.
"Perianth Phyllotaxis Is polymorphic in the basal eudicot Anemone and Eranthis species."
Frontiers in Ecology Evolution (2020) doi.org/10.3389/fevo.2020.00070
朝日新聞.
Nakagawa A#., Kitazawa M. S#., Fujimoto K. (#Equal contribution)
"A design principle for floral organ number and arrangement in flowers with bilateral symmetry."
Development (2020) doi: 10.1242/dev.182907
RESEARCH HIGHLIGHT.
プレスリリース 阪大ReSOU. 朝日新聞.

2019

Matsushita K., Horibe K., Kamamoto N., Yabunaka S.,Fujimoto K.
"Crowding-Boosting Polarity and Motion Order of Cells"
Proceedings of the Symposium on Simulation of Traffic Flow (2019) 25, 21--24
Hironaka K., Fujimoto K., Nishimura T.
"Optimal scaling of critical size for metamorphosis in the genus Drosophila."
iScience (2019) 20(25): 348-358. DOI: 10.1016/j.isci.2019.09.033
プレスリリース 阪大ReSOU, 理研.
Matsushita K., Horibe K., Kamamoto N., Fujimoto K.
"Cell Motion Alignment as a Polarity Memory Effect."
J. Phys. Soc. Jpn. (2019) 88(10): 103801. DOI: 10.7566/JPSJ.88.103801
Horibe K., Hironaka K., Matsushita K., Fujimoto K.
"Curved surface geometry-induced topological change of an excitable planar wavefront."
Chaos (2019) 29: 093120.
Toyokura K.#, Goh T.#, Shinohara H., Shinoda A., Kondo Y., Okamoto Y., Uehara T., Fujimoto K., Okushima Y., Ikeyama Y., Nakajima K., Mimura T., Tasaka M., Matsubayashi Y., and Fukaki H. (#Equal contribution)
"Lateral Inhibition by a Peptide Hormone-Receptor Cascade during Arabidopsis Lateral Root Founder Cell Formation."
Developmental Cell (2019) 48(1): P64-75.e5
Preview.
プレスリリース.

2018

Tsuboi A., Ohsawa S., Umetsu D., Sando Y., Kuranaga E., Igaki T., Fujimoto K.
"Competition for Space Is Controlled by Apoptosis-Induced Change of Local Epithelial Topology."
Curr. Biol. (2018) 28(13): 2115.
Dispatch.
EurekAlert!. AlphaGelileo. Phys.Org. Science Daily.
プレスリリース. 日刊工業新聞. 朝日新聞. 科学新聞.
Matsushita K., Horibe K., Kamamoto N. and Fujimoto K.
"Cell Migration driven by Receptor Density Polarity of Cell-Matrix Adhesion."
Proceedings of the Symposium on Simulation of Traffic Flow (2018) 24: 5-8
Matsushita K.
"Emergence of collective propulsion through cell-cell adhesion."
Physical Review E (2018) 97(4): 042413(5)
Kitazawa M. S., Fujimoto K.
"Spiral phyllotaxis underlies constrained variation in Anemone (Ranunculaceae) tepal arrangement."
J. Plant Res. (2018) 131(3):459-468
Nakamura K., Hisanaga T., Fujimoto K., Nakajima K., Wada H.
"Plant-inspired pipettes"
J. Roy. Soc. Interface (2018) 15:20170868.
Please visit also Science News.
Hemmi N., Akiyama-Oda Y., Fujimoto K., Oda H.
"A quantitative study of the diversity of stripeforming processes in an arthropod cell-based field undergoing axis formation and growth"
Dev. Biol. (2018) 437(2): 84-104.
The winner of DB Outstanding Paper Award 2018.
Scientific presentation made by Hemmi Natsuki, M.S.
Selected as the cover image.
See also Science Trends.

2017

Katsuyoshi Matsushita
"Elementary movement step of adhesive-interaction driving cells"
Proceedings of symposium on simulations of traffic flow 23, (2017), 37-40
Daisuke Mashiko, Masahito Ikawa, Koichi Fujimoto
"Mouse spermatozoa with higher fertilization rates have thinner nuclei"
PeerJ. (2017) 5:e3913.
Alice Tsuboi#, Daiki Umetsu#*, Erina Kuranaga, Koichi Fujimoto* (#Equal contribution, *Correspondence)
"Inference of cell mechanics in heterogeneous epithelial tissue based on multivariate clone shape quantification"
Frontiers in Cell and Developmental Biology. (2017) 5:68.
Yoshihiro Morishita, Ken-ichi Hironaka, Sang-Woo Lee, Takashi Jin, Daisuke Ohtsuka
"Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells"
Nature Communications (2017) 8: 15.
Katsuyoshi Matsushita
"Cell-alignment patterns in the collective migration of cells with polarized adhesion"
Physical Review E (2017) 95: 032415.
Ken-ichi Hironaka, Yoshihiro Morishita
"Adaptive significance of critical weight for metamorphosis in holometabolous insects"
Journal of Theoretical Biology (2017) 417: 68-83.

2016

Kitazawa M. S., Fujimoto K.
"Stochastic occurrence of trimery from pentamery in floral phyllotaxis of Anemone (Ranunculaceae)"
Acta Soc. Bot. Poloniae (2016) 85(4): 3530.
Kitazawa M. S., Fujimoto K.
"Relationship between the species-representative phenotype and intraspecific variation in Ranunculaceae floral organ and Asteraceae flower numbers"
Annals of Botany (2016) 117(5): 925-935.
Selected as Cover Image of special issue on "DEVELOPMENTAL ROBUSTNESS AND SPECIES DIVERSITY".
Please visit also AoBBlog.
Sato, Y., Shimaoka,D., Fujimoto, K., Taga G.
"Neural field dynamics for growing brains"
Nonlinear Theory and Its Applications (2016) 7(2): 226-233.
Haruhiko Miyata, Julio M Castaneda, Yoshitaka Fujihara, Zhifeng Yu, Denise R Archambeault, Ayako Isotani, Daiji Kiyozumi, Maya L Kriseman, Daisuke Mashiko, Takafumi Matsumura, Ryan M Matzuk, Masashi Mori, Taichi Noda, Asami Oji, Masaru Okabe, Renata Prunskaite-Hyyrylainen, Ramiro Ramirez-Solis, Yuhkoh Satouh, Qian Zhang, Masahito Ikawa, Martin M Matzuk
"Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice"
Proceedings of the National Academy of Sciences (2016) 113(28): 7704-7710.
Katsuyoshi Matsushita.
"Model Prediction of Cell-Shape Dependence of Cell Motion"
Proceedings of the Symposium on Simulation of Traffic Flow (2016) 22: 5-8.

2015

Kitazawa M. S., Fujimoto K.
"A Dynamical Phyllotaxis Model to Determine Floral Organ Number"
PLoS Compulational Biology (2015) 11(5): e1004145.
Haruhiko Miyata, Yuhkoh Satouh, Daisuke Mashiko, Masanaga Muto, Kaori Nozawa, Kogiku Shiba, Yoshitaka Fujihara, Ayako Isotani, Kazuo Inaba, Masahito Ikawa.
"Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive"
Science (2015) 350(6259): 442-445.
Katsuyoshi Matsushita.
"Collective Migration of Repulsively Interacting Cells"
Proceedings of the Symposium on Simulation of Traffic Flow (2015) 21: 19-22.

2014

Kitazawa M. S., Fujimoto K.
"A Developmental basis for stochasticity in floral organ numbers"
Frontiers in Plant Science (2014) 5, 545

2013

Fujimoto K., Sawai S.
“A Design Principle of Group-level Decision Making in Cell Populations”
PLoS Computational Biology (2013) 9(6), e1003110.
Masaki N.*, Fujimoto K.*, Honda-Kitahara M, Hada M., Sawai S. (*Equal contribution)
“Robustness of Self-Organizing Chemoattractant Field Arising from Precise Pulse Induction of Its Breakdown Enzyme: A Single-Cell Level Analysis of PDE Expression in Dictyostelium”
Biophys. J. (2013) 104, 1191 - 1202.

2011

Ode K. L., Fujimoto K, Kubota Y., and Takisawa H.
“Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing”
Genes Cells (2011) 16, 380 - 396.

2010

Gregor T., Fujimoto K, Masaki N. and Sawai S.
“The Onset of Collective Behavior in Social Amoebae”
Science (2010) 328, 1021-1025.

2008

Fujimoto K., Ishihara S. and Kaneko K.
“Network evolution of body plans.”
PLoS ONE. (2008) e2772.

~2007

Tachikawa M. and Fujimoto K.
“Emergence of multi-time scales in coupled oscillators with plastic frequencies.”
Europhysics Letters (2007) 78, 20004.
Matsuo M., Fujimoto K. and Shibata T.
“Relation between Adaptation and Irrversible Circulation in Bacteria Chemotaxis.”
Progress of Theoretical Physics Suppl. (2006) 161, 251-254.
Ishihara S., Fujimoto K. and Shibata T.
“Cross talking of network motifs in gene regulation that generates temporal pulses and spatial stripes.”
Genes Cells (2005) 10, 1025-38
Shibata T. and Koichi Fujimoto K.
“Noisy signal amplification in ultrasensitive signal transduction.”
Proc. Natl. Acad. Sci. USA. (2005) 102, 331-6.
Fujimoto K. and Kaneko K.
“Convective instability with time scale translation of the transmitted fluctuation.”
Physica D (2004) 196, 67-89.
Fujimoto K. and Kaneko K.
“How fast elements can affect slow dynamics.”
Physica D (2003) 180, 1-16.
Fujimoto K. and Kaneko K.
“Bifurcation cascade as chaotic itinerancy with multiple time scales.”
Chaos (2003) 13, 1041-1056.
Fujimoto K. and Kaneko K.
“Sensitive boundary condition dependence of noise-sustained structure.”
Physical Review E (2001) 63, 0362180-1-5.
Fujimoto K. and Kaneko K.
“Noise-induced input dependence in a convectively unstable dynamical System.”
Physica D (1999) 129, 203-222.

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Reviews

2019

北沢 美帆
“ばらつきから見えること:キンポウゲ科の花被片数を例に”
BSJ-Review (2019) DOI: 10.24480/bsj-review.10a5.00152
北沢 美帆, 藤本 仰一
“花の器官数を決める数理”
生物物理 (2019) 59(5): 266-270.

2018

坪井有寿、藤本 仰一
“前がん細胞が正常細胞の領地へ拡大して占拠するしくみ - 予測と検証.”
実験医学 (2018) 12月号 3282-3285.

2017

藤本 仰一
“生命の物理:相互干渉する多スケール系の共通性と多様性.”
日本物理学会誌 特集「物理学70の不思議」 (2017) 3月号.

2016

北沢 美帆, 藤本 仰一
“花びらが7枚の花はなぜ少ないか”
パリティ (2016)12月号 31(12): 4-10.
坪井 有寿, 藤本 仰一
“アポトーシスにより空いた隙間をめぐる力学的な細胞競合──数理モデルからの予測”
医学のあゆみ 特集 "細胞競合の基本原理とその破綻" (2016) 257(4): 311-316.
坪井 有寿, 藤本 仰一
“機械的な力を介した細胞競合の数理モデル”
生体の科学 特集 "細胞の社会学″ラ胞間で繰り広げられる協調と競争" (2016) 67(2): 159-162.

2012

Fujimoto K., Sawai S.
“Collective Decision making and oscillatory behaviors in cell populations”
Engineering Chemical Complexity. (World Scientific Pub. Singapore. Edited by Mikhailov & Ertl) (2012) 279-298.

2011

Kamino K., Fujimoto K., Sawai S.
“The collective oscillations in developing cells: Insights from simple systems”
Dev. Growth Dif. (2011) 53, 503 - 517.

2010

藤本 仰一, 石原 秀至, 金子 邦彦
“空間パタン形成の遺伝子ネットワーク進化理論 ― ネットワーク構造と機能の対応づけ.”
生物物理 (2010) 50, 18-22.

2009

藤本 仰一
“体節形成パターンを数理モデルで解く.”
生命誌ジャーナル (2009) 夏号

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